The search to find Savannah Guthrie’s missing mother, Nancy Guthrie, is “a race against time,” according to Pima County Sheriff Chris Nanos.
Nanos appeared during the Tuesday, February 3, broadcast of the Today show and said he hopes “that window hasn’t closed” as the investigation into 84-year-old Nancy’s disappearance continues.
“We took some samples that we hope will have enough profile of a DNA profile that gives us some identification of what we’re looking at,” Nanos added, noting that it might be a few more days before any evidence comes from the samples being tested.
News broke on Sunday, February 1, that Nancy had been reported missing in Arizona. She was last seen on Saturday, January 31.
“We can confirm this is a missing persons case, and the family is working closely with local law enforcement,” the Guthrie family shared in a statement on Monday.
During a press conference on Sunday, Nanos called the situation “very concerning,” revealing that authorities haven’t ruled out foul play. In a second press conference, which took place on Monday, February 2, authorities confirmed that Nancy is in need of daily medication and has mobility issues.
“Nancy Guthrie is of great, sound mind. This is not dementia-related. She is as sharp as a tack,” Nanos said. “The family wants everybody to know this isn’t somebody who just wandered off.”
He offered more information during an exclusive interview with Us Weekly on Monday.
“Something unusual at that house occurred that made us go, ‘Wow, something’s wrong here. Something doesn’t fit,’” Nanos said. “We’re gonna pull all the stops and go at all angles. We really do hope it’s a search-and-rescue mission and we find her and she’s safe and sound. But it would be unjust if we didn’t look at what’s in front of us and go, ‘We need to act.’”
He added, “This is an 84-year-old lady who is safe in her own home asleep, and she is taken. And that should never happen.”
Nanos confirmed to Us that Nancy’s family “really wants her back.”
Savannah has been absent from the Today show this week as she traveled to Arizona amid Nancy’s disappearance. The NBC anchor issued a statement via Instagram Monday night.
“We believe in prayer. we believe in voices raised in unison, in love, in hope. we believe in goodness. we believe in humanity. above all, we believe in Him,” Savannah wrote on Instagram alongside a graphic that read, “Please Pray.”
Her caption continued, “Thank you for lifting your prayers with ours for our beloved mom, our dearest Nancy, a woman of deep conviction, a good and faithful servant. raise your prayers with us and believe with us that she will be lifted by them in this very moment.”
Savannah previously shared a statement with her colleagues, which was released during the Today broadcast on Monday.
“On behalf of our family, I want to thank everyone for the thoughts, prayers and messages of support,” the statement read. “Right now, our focus remains on the safe return of our dear mom. We thank law enforcement for their hard work on this case and encourage anyone with information to contact the Pima County Sheriff’s Department.”
In a separate interview with CBS News on Monday, Nanos said that he believes Nancy was “abducted” from her home.
“She didn’t walk from there,” he added. “She didn’t go willingly.”

